Joseph M. Bowler

Joseph M. Bowler, PhD

Associate | Biotechnology
617.646.8393 LinkedIn Profile


  • BA, Bellarmine University
  • PhD, Biochemistry, Florida State University
  • JD, Suffolk University Law School

Key Technologies

  • DNA and Protein Sequencing
  • Library Preparation for Sequencing
  • Nucleic Acid and Protein Products
  • Protein Manufacturing
  • Precision Medicine
  • Assay Platform Technologies

Practice Groups

Admitted to Practice

  • Massachusetts
  • US Patent and Trademark Office


  • Boston


Joseph Bowler focuses his practice on patent prosecution and counseling in the areas of life sciences and biotechnology. He has extensive knowledge and experience in technologies relating to nucleic acid and protein products, next-generation sequencing, and single-molecule assays.

Joseph works with clients in industry and academia to obtain patent protection in the US and abroad.  He has comprehensive experience in patent preparation and prosecution, as well as patentability and freedom-to-operate analyses, and patent portfolio management.

Joseph's doctoral research involved investigating the mechanism of allosteric activation of glucokinase, an enzyme that regulates glucose homeostasis and insulin secretion.


  • Boston Intellectual Property Law Association


  • Joseph M. Schor Fellowship in Biochemistry, Florida State University
  • Trustee Academic Scholarship, Suffolk University Law School


Scientific Publications

  • Whittington AC, Larion M, Bowler JM, Ramsey KM, Brüschweiler R, Miller BG. (2015) Dual allosteric activation mechanisms in monomeric human glucokinase. Proc Natl Acad Sci USA. 15;112(37):11553-8. 
  • Bowler JM, Hervert KL, Kearley ML, Miller BG. (2013) Small-Molecule Allosteric Activation of Human Glucokinase in the Absence of Glucose. ACS Med Chem Lett. 5;4(7).
  • Xiao Q, Jackson JJ, Basak A, Bowler JM, Miller BG, Zakarian A. (2013) Enantioselective synthesis of tatanans A-C and reinvestigation of their glucokinase-activating properties. Nat Chem. 5(5):410-6.