Danielle C. Samblanet

Danielle C. Samblanet, PhD

Associate | Pharmaceutical
617.646.8565 Danielle.Samblanet@WolfGreenfield.com LinkedIn Profile


  • BS, Chemistry, The University of Toledo, magna cum laude
  • MS, Chemistry, University of Michigan
  • PhD, Chemistry, University of Michigan
  • JD, Suffolk University Law School

Key Technologies

  • Small Molecules
  • Solid Forms (e.g., Polymorphs)
  • Polymers
  • Compositions
  • Formulations
  • Dosing Regimens
  • Drug Delivery Systems
  • Novel Uses of Known Agents
  • Chemical Synthesis
  • Process Chemistry

Practice Groups

Admitted to Practice

  • Ohio
  • US Patent and Trademark Office


Danielle assists the firm in patent prosecution in the areas of pharmaceutical, chemical, and biochemical technologies by strategizing and implementing ways to protect client’s intellectual property. She assists in managing patent portfolios for universities, companies (e.g., pharmaceutical companies, start-up companies), and venture capital firms. She has experience in drafting and prosecuting patent applications, preparing freedom-to-operate and patentability analyses, and assisting in opinion work including patent invalidity and infringement/non-infringement opinions. 

Danielle has extensive knowledge and experience in the areas of organic chemistry, inorganic chemistry, materials chemistry, polymer chemistry, synthetic chemistry, and more.

Prior to joining Wolf Greenfield, Danielle obtained her PhD in chemistry at the University of Michigan under Melanie S. Sanford. Her doctoral research focused on carbon dioxide utilization and catalysis, specifically on homogeneous, heterogeneous, and heterogenized-homogeneous catalytic hydrogenation for cascade conversion of carbon dioxide to methanol. 

Danielle completed her undergraduate studies in chemistry at the University of Toledo. During this time, she studied C-N bond forming reactions including hydroamination and aryl amination.


  • Assist in managing patent portfolios for universities, pharmaceutical companies, and research, including late-stage clinical candidates.
  • Prepare pharmaceutical and biotechnology patent applications relating to a wide range of technologies including small molecules (e.g., new chemical entities, solid forms), polymers, and pharmaceuticals (e.g., formulations, dosing regimens).
  • Prosecute patent applications before the USPTO and work closely with foreign associates to prosecute patent applications before global patent offices.
  • Conduct patentability and freedom-to-operate analyses.
  • Assist in opinion work including patent invalidity and infringement/non-infringement opinions.


  • Academic Leadership Scholarship, Suffolk University Law School
  • Trustee Academic Scholarship, Suffolk University Law School 
  • Jurisprudence Award in Antitrust, Suffolk University Law School
  • Best Brief Award in Legal Practice Skills, Suffolk University Law School
  • National Science Foundation Graduate Research Fellowship Program Honorable Mention
  • National Science Foundation Scholar Award
  • ACS Division of Inorganic Chemistry Outstanding Undergraduate Student Award
  • American Institute of Chemists Foundation Outstanding Graduating Senior Award


  • “Iron-Catalyzed Hydrogenation of Amides to Alcohols and Amines,” ACS Catal. 2016, 6, 6377–6383. 
  • “Rhodium Hydrogenation Catalysts Supported in Metal Organic Frameworks: Influence of the Framework on Catalytic Activity and Selectivity,” ACS Catal. 2016, 6, 3569–3574. 
  • “The Electronic Role of 3-Iminophosphine Ligands in Palladium-Catalyzed Intermolecular Hydroamination,” Organometallics 2015, 34, 1809–1817. 
  • “Palladium Catalyzed Intermolecular Hydroamination of 1- Substituted Allenes: An Atom-Economical Method for the Synthesis of N-Allylamines,” RSC Adv. 2013, 3, 20708–20718. 
  • “Efficient Catalytic Aryl Amination of Bromoarenes Using 3-Iminophosphine Palladium(II) Chloride Complexes,” J. Organomet. Chem. 2012, 720, 7–18.