Overview
Téa Tsaava assists the firm in biotechnology patent prosecution. Téa has extensive knowledge in the areas of bioelectronic medicine, neuroscience, neuropathology, immunology, and biomedical engineering.
Prior to joining Wolf Greenfield, Téa was a research scientist with over 15 years of experience. She previously served as s a Senior Research Assistant in the Laboratory of Biomedical Science at The Feinstein Institutes for Medical Research at Northwell Health, where she studied the neuroscience of immunity. Her research was aimed at establishing the molecular basis of neuro-immune interactions needed to develop new devices to treat disease.
Activities
- Society for Neuroscience
- New York Academy of Sciences
- American Association of Immunologists
- The Shock Society
Scientific Publications
- Tsaava T. Toxicity of pesticide formulations to soil bacteria. MS thesis Adelphi University, New York, 2008.
- Weeks BS, Lee S, Perez PP, Brown K, Chauhan H, Tsaava T. Natramune and PureWay-C reduce xenobiotic-induced human Tcell alpha5beta1 integrin-mediated adhesion to fibronectin. Medical Science Monitor 14(12): BR279-85, 2008.
- Bach H, Arango V, Kassir SA, Tsaava T, Dwork AJ, Mann JJ, Underwood MD. Alcoholics have more Tryptophan Hydroxylase 2 mRNA and Protein in the Dorsal and Median Raphe Nuclei. Alcoholism: Clinical and Experimental Research, 38(7),1894–1901, 2014.
- Ju Z, Chavan SS, Antoine DJ, Dancho M, Tsaava T, Li J, Lu B, Levine YA, Stiegler A, Tamari Y, Al-Abed Y, Roth J, Tracey KJ, Yang, H. Sequestering HMGB1 via DNA-Conjugated Beads Ameliorates Murine Colitis. PLoSONE, 9(8), e103992, 2014.
- Steinberg BE, Silverman HA, Robbiati S, Gunasekaran M, Tsaava T, Battinelli E, Stiegler A, Bouton CE, Chavan SS, Tracey KJ, Huerta PT. Cytokine-specific neurograms in the sensory vagus nerve. Bioelectronic Medicine vol3, 7-17, 2016.
- Hanes WM, Olofsson PS, Talbot S, Tsaava T, Ochani M, Imperato GH, Levine YA., Roth J, Pascal MA, Foster SL, Wang P, Woolf C, Chavan SS, Tracey KJ. Neuronal circuits modulate antigen flow through lymph nodes. Journal of Bioelectronic Medicine vol3, 18-29, 2016.
- Caravaca AS, Tsaava T, Goldman L, Silverman H, Riggott G, Chavan SS, Bouton C, Tracey KJ, Desimone R, Boyden E, Sohal HS, Olofsson PS. A novel flexible cuff-like microelectrode for dual purpose, acute and chronic electrical interfacing with the mouse cervical vagus nerve. Journal of Neural Engineering 14(6):066005, 2017.
- Silverman HS, Stiegler A, Tsaava T, Newman J, Steinberg BE, Masi EB, Robbiati S, Bouton C, Huerta PT, Chavan SS, Tracey KJ. Standardization of methods to record vagus nerve activity in mice. Bioelectronic Medicine 4:3, 2018.
- Zanos TP, Silverman HA, Levy T, Tsaava T, Battinelli E, Lorraine PW, Ashe JM, Chavan SS, Tracey KJ, Bouton CE. Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity. Proceedings of the National Academy of Sciences May 2018, 201719083.
- Levy TJ, Ahmed U, Tsaava T, Chang YC, Lorraine PJ, Tomaio JN, Cracchiolo M, Lopez M, Rieth L, Tracey KJ, Zanos S, Zanos TP. An impedance matching algorithm for common-mode interference removal in vagus nerve recordings. J Neurosci Methods. 2020 Jan 15;330:108467.
- Tsaava T, Datta-Chaudhuri T, Addorisio ME, Masi EB, Silverman HA, Newman JE, Imperato GH, Bouton C, Tracey KJ, Chavan SS, Chang EH. Specific vagus nerve stimulation parameters alter serum cytokine levels in the absence of inflammation. Bioelectronic Medicine. 2020 Apr 10;6:8.
- Cotero V, Fan Y, Tsaava T, Kressel AM, Hancu I, Fitzgerald P, Wallace K, Kaanumalle S, Graf J, Rigby W, Kao TJ, Roberts J, Bhushan C, Joel S, Coleman TR, Zanos S, Tracey KJ, Ashe J, Chavan SS, Puleo C. Noninvasive sub-organ ultrasound stimulation for targeted neuromodulation. Nature Communications. 2019 Mar 12;10(1):952.
- Chu C, Murdock MH, Jing D, Won TH, Chung H, Kressel AM, Tsaava T, Addorisio ME, Putzel GG, Zhou L, Bessman NJ, Yang R, Moriyama S, Parkhurst CN, Li A, Meyer HC, Teng F, Chavan SS, Tracey KJ, Regev A, Schroeder FC, Lee FS, Liston C, Artis D. The microbiota regulate neuronal function and fear extinction learning. Nature. 2019 Oct;574(7779):543-548.
- Kressel AM, Tsaava T, Levine YA, Chang EH, Addorisio ME, Chang Q, Burbach BJ, Carnevale D, Lembo G, Zador AM, Andersson U, Pavlov VA, Chavan SS, Tracey KJ. Identification of a Brainstem Locus That Inhibits Tumor Necrosis Factor. Proceedings of the National Academy of Sciences 2020, Nov 24; 117(47):29803-29810.
- Huerta TS, Devarajan A, Tsaava T, Rishi A, Cotero V, Puleo C, Ashe J, Coleman TR, Chang EH, Tracey KJ, Chavan SS. Targeted peripheral focused ultrasound stimulation attenuates obesity-induced metabolic and inflammatory dysfunctions. Nature: Scientific Reports. 2021 Mar 3;11(1):5083. DOI: 10.1038/s41598-021-84330-6.
- Yang H, Zeng Q, Silverman HA, Gunasekaran M, George SJ, Devarajan A, Addorisio ME, Li J, Tsaava T, Shah V, Billiar TR, Wang H, Brines M, Andersson U, Pavlov VA, Chang EH, Chavan SS, Tracey KJ. HMGB1 released from nociceptors mediates inflammation. Proceedings of National Academy of Sciences, 2021 Aug 17;118(33): e2102034118.
- Stiegler A, Li JH, Shah V, Tsaava T, Tynan A, Yang H, Tamari Y, Brines M, Tracey KJ, Chavan SS. Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension. Mol Med. 2021 Oct 21;27(1):133