Oona Johnstone focuses her practice on US and foreign patent prosecution, IP due diligence, client counseling and post-grant proceedings, including inter partes review (IPR), in the areas of biotechnology, pharmaceuticals and cleantech. Her knowledge spans a wide range of technologies including RNA-based therapeutics, transgenics, antibodies, immune-modulating agents, metabolic engineering, systems and synthetic biology, and drug delivery.

Oona has experience advising clients on maximizing patent term through patent term adjustment (PTA), patent term extension (PTE) and Supplementary Protection Certificates (SPCs).

Oona additionally has experience advising clients on biosimilar/biobetter issues.

Prior to joining Wolf Greenfield, Oona was a postdoctoral researcher in the Department of Systems Biology at Harvard Medical School. Her research, focusing on posttranscriptional gene regulation, was part of a large-scale initiative to use genome-wide technologies to characterize networks of RNA-protein interactions in the developing mammalian brain.

Oona’s doctoral research on RNA helicases helped to elucidate cell biological questions related to RNA localization and translational regulation, while placing these mechanistic insights within the context of the developing embryo.

Oona has authored and co-authored publications in journals including Molecular Cell, Development, Developmental Biology, International Review of Cytology, and Annual Review of Genetics.

Prepared and prosecuted patent portfolios for corporate, academic, and non-profit institutions
Worked closely with early-stage biotech company to evaluate competitor activity, provide freedom-to-operate and non-infringement analysis, and develop strategy for achieving worldwide patent protection
Provided IP due diligence and regulatory analysis for multiple biotech/pharma transactions
Conducted patent landscape studies and counseled pharmaceutical company on strategy for biosimilar product development
Advised clients on inter partes review (IPR) strategy, including drafting IPR Petitions and Patent Owner Preliminary Responses
Represented Patent Owner BTG International Inc. in an IPR proceeding. Obtained denial of institution.
Successfully represented Patent Owner in achieving denial of institution of four IPR proceedings in RNA interference technology
Conducted pre-suit investigation involving analysis of competitor’s product to demonstrate infringement of client’s claims
Successfully appealed written description rejection of antibody claims to the Patent Trial and Appeal Board (PTAB) of the US Patent and Trademark Office

Boston Patent Law Association
Leadership Council on Legal Diversity
Women Entrepreneurs in Science and Technology
Women in Bio

Oona is a finalist in the “US Rising Star - Intellectual Property” category for the LMG Life Sciences Awards 2020. Oona is one of only five attorneys recognized in this category. Oona has been repeatedly named one of Massachusetts Super Lawyers' "Rising Stars" in the field of intellectual property law.

Oona was awarded a Doctoral Studentship and a Postdoctoral Fellowship from the Canadian Institutes of Health Research. In law school, she received Best Oral Advocate and Distinguished Legal Brief awards in her Legal Practice Skills class. She also participated in the Walter H. McLaughlin Appellate Advocacy Competition.

Scientific Publications

Gamberi C, Johnstone O, Lasko P. (2006) Drosophila RNA binding proteins. Int Rev Cytol. 248:43-139.

Johnstone O, Deuring R, Bock R, Linder P, Fuller MT, Lasko P. (2005) Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol. 1;277(1):92-101.

Johnstone O, Lasko P. (2004) Interaction with eIF5B is essential for Vasa function during development. Development. 131(17):4167-78.

Johnstone O, Lasko P. (2001) Translational regulation and RNA localization in Drosophila oocytes and embryos. Annu Rev Genet. 35:365-406.

Carrera P, Johnstone O, Nakamura A, Casanova J, Jäckle H, Lasko P. (2000) Mol Cell. 5(1):181-7.